Southern Africa

VIDEO: South African doctor cures deafness with first-ever middle ear transplant

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Professor Mashudu Tshifularo

A team of South African doctors in Pretoria, led by Professor Mashudu Tshifularo, have successfully performed the first-ever transplant of a middle ear.

For ten years, Professor Mashudu Tshifularo, had been studying conductive hearing loss, including the use of 3D printing technologies for the purpose of scanning and wholly recreating the smallest bones, or ossicles, of the middle ear–namely the hammer, anvil and stirrup.

The team used a 3D-printed technology to reconstruct the broken bones of a middle ear, making it a long-term solution to conductive hearing loss. Doctors say the surgery can be performed on people of any age, including newborn babies.

This pioneering surgical procedure using 3D-printed middle ear bones, developed by Professor Mashudu Tshifularo and his team at the University of Pretoria (UP) Faculty of Health, may be the answer to conductive hearing loss, a middle ear problem caused by congenital birth defects, infection, trauma or metabolic diseases. 

40-year-old Thabo Molishiwa, whose middle ear was completely damaged in a car accident, is the first patient to undergo this surgery and can now hear again. Due to the nature of his trauma, the operation lasted about an hour and a half.

The procedure effectively replaces the hammer, anvil, and stirrup, the ossicles (smallest bones in the body) that make up the middle ear. 3D-printing technology was used to print these bones and then used in the surgery to reconstruct the ossicles. 

“By replacing only the ossicles that aren’t functioning properly, the procedure carries significantly less risk than known prostheses and their associated surgical procedures,” Prof Tshifularo explains.

“We will use titanium for this procedure, which is biocompatible. We use an endoscope to do the replacement, so the transplant is expected to be quick, with minimal scarring,” he added.

According to the South African Hearing Institute, our hearing ability naturally declines from age 30 or 40. In fact, by age 80, more than half of humans will suffer from significant hearing loss. While hearing loss is a natural part of ageing, it could also occur as a result of disease or infection. It may also be inherited or be the result of physical damage to the ears or head.  

The surgery also aims to simplify the reconstruction of ossicles during middle ear procedures, such as ossiculoplasty and stapedectomy, in order to increase the chance of success with minimal intrusion trauma.

Professor Mashudu Tshifularo, HOD of Otorhinolaryngology at the Steve Biko Academic Hospital holding a model of the middle ear. Picture: Thapelo Morebudi/The Sunday Times.

In addition, Prof Tshifularo’s procedure reduces the chance of facial nerve paralysis, which can occur if the facial nerve that passes through the middle ear space is damaged during traditional surgery. 

South African President Ramaphosa celebrates the medical breakthrough

“3D technology is allowing us to do things we never thought we could,” says Prof Tshifularo, who is head of the Department of Otorhinolaryngology (Ear, Nose and Throat) at UP. “But I need sponsors and funding for this invention to take off the ground.” 

Patient, Thabo Molishiwa recovering

For Prof Tshifularo, “innovate or perish” are words to live by when it comes to clinical procedures, teaching, research and medical devices, and believes that academics have a responsibility to come up with solutions that benefit communities

“As a Department of Health, we shall do everything in our power to assist and mobilize resources to make sure that Prof. Tshifularo gets all the help he needs for this far-reaching innovation”, said Minister Motsoaledi.  The Minister also calls upon donors and development partners, especially the business community in South Africa to support this, South Africa’s scientific breakthrough.

1 Comment

  1. Its a good Development, But it will be more better the country starts and implement a campaign on this effect.

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